| Identification | Back Directory | [Name]
SB 222200 | [CAS]
174635-69-9 | [Synonyms]
CS-1124
SB 222200
SB-222200; SB222200
(S)-3-METHYL-2-PHENYL-N-(1-PHENYLPROPYL)-4-QUINOLINECARBOXAMIDE
3-METHYL-2-PHENYL-N-[(1S)-1-PHENYLPROPYL]-4-QUINOLINECARBOXAMIDE
3-Methyl-2-phenyl-N-((1S)-1-phenylpropyl)quinoline-4-carboxamide
4-Quinolinecarboxamide, 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-
SB222200//3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxaMide | [Molecular Formula]
C26H24N2O | [MDL Number]
MFCD00944072 | [MOL File]
174635-69-9.mol | [Molecular Weight]
380.48 |
| Chemical Properties | Back Directory | [Melting point ]
154℃ | [Boiling point ]
553.5±50.0 °C(Predicted) | [density ]
1.142 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO: ~28 mg/mL, soluble
| [form ]
solid
| [pka]
12.88±0.46(Predicted) | [color ]
light yellow
|
| Hazard Information | Back Directory | [Uses]
3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a chemical agent used in the preparation of acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor as antipsychotics (1,2). | [Definition]
ChEBI: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines. | [Biological Activity]
Potent and selective non-peptide NK 3 receptor antagonist. K i values are 4.4, >100,000 and 250 nM for human NK 3 , NK 1 and NK 2 receptors respectively. Brain penetrant and active in vivo . | [storage]
Store at RT |
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| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
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