| Identification | Back Directory | [Name]
13C,16C-DOCOSADIENOIC ACID | [CAS]
17735-98-7 | [Synonyms]
C22:2
13Z,16Z-Docosadienoic Acid
13C,16C-DOCOSADIENOIC ACID
13-CIS,16-CIS-DOCOSADIENOIC ACID
13,16-Docosadienoic acid, (13Z,16Z)-
DELTA 13 CIS 16 CIS DOCOSADIENOIC ACID | [Molecular Formula]
C22H40O2 | [MDL Number]
MFCD00673434 | [MOL File]
17735-98-7.mol | [Molecular Weight]
336.55 |
| Chemical Properties | Back Directory | [Boiling point ]
456.3±14.0 °C(Predicted) | [density ]
0.900±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
≤10mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide | [form ]
solution in ethanol. | [pka]
4.78±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
13Z,16Z-Docosadienoic acid is a natural ω-6 polyunsaturated fatty acid (PUFA). It is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells. This 20:2 PUFA has been identified in mammals, fish, plants, and anaerobic fungi. | [Uses]
13(Z),16(Z)-Docosadienoic Acid, is a natural polysaturated fatty acid found in mammals, fish, plants, and anaerobic fungi. It is also an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells. | [Definition]
ChEBI: (13Z,16Z)-docosadienoic acid is a docosadienoic acid having two cis-double bonds at position 13 and 16 respectively. It has a role as a metabolite. It is a conjugate acid of a (13Z,16Z)-docosadienoate. | [References]
[1]. x. lu, x. zhao, j. feng, et al. postprandial inhibition of gastric ghrelin secretion by long-chain fatty acid through gpr120 in isolated gastric ghrelin cells and mice. am. j. physiol. gastrointest. liver physiol. 303(3), g367-376 (2012).
[2]. kimura i. omega-3 fatty acids and ffar4[j]. obesity and diabetes: energy regulation by free fatty acid receptors, 2016: 29.
[3]. ma d w l, seo j, switzer k c, et al. n-3 pufa and membrane microdomains: a new frontier in bioactive lipid research[j]. the journal of nutritional biochemistry, 2004, 15(11): 700-706. |
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