| Identification | Back Directory | [Name]
3-Hydroxybakuchiol | [CAS]
178765-54-3 | [Synonyms]
3-Hydroxybakuchiol
4-[(1E,3S)-3-ethenyl-3,7-dimethylocta-1,6-dienyl] benzene-1,2-diol
4-[(1E,3S)-3-Ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-1,2-benzenediol
1,2-Benzenediol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]- | [Molecular Formula]
C18H24O2 | [MOL File]
178765-54-3.mol | [Molecular Weight]
272.38 |
| Hazard Information | Back Directory | [Uses]
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2]. | [References]
[1] Ja?a F, et al. Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64. DOI:10.1016/j.taap.2013.06.005
[2] Suárez AI, et al. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Nat Prod Commun. 2017 Apr;12(4):533-535. PMID:30520590 |
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