| Chemical Properties | Back Directory | [Boiling point ]
726.2±70.0 °C(Predicted) | [density ]
1.415±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.87±0.30(Predicted) | [color ]
Off-White to Light Yellow | [CAS DataBase Reference]
1792999-26-8 |
| Hazard Information | Back Directory | [Uses]
cis-4-?[[2-?(1H-?Benzimidazol-?6-?ylamino)?-?8-?quinazolinyl]?oxy]?-?cyclohexanol inhibits Traf2 and Nck-interacting protein kinase (TNIK). TNIK is involved with Canonical Wnt/b-catenin signalling, which has regulatory roles in maintaining intestinal stem cells and aberration in this pathway has been implicated in colorectal carcinogenesis. TNIK is a therapeutic target. | [storage]
Store at -20°C |
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