ChemicalBook--->CAS DataBase List--->179420-17-8

179420-17-8

179420-17-8 Structure

179420-17-8 Structure
IdentificationBack Directory
[Name]

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
[CAS]

179420-17-8
[Synonyms]

CJ-13610
CJ-13610 (CJ13610)
CJ-13610 >=98% (HPLC)
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-
4-(3-((4-(2-METHYL-1H-IMIDAZOL-1-YL)PHENYL)SULFANYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
Lipoxygenase,inhibit,CJ 13,610,LOX,nonredox-type,polymorphonuclear leukocytes,Inhibitor,CJ-13,610,arachidonic acid,CJ13,610
[Molecular Formula]

C22H23N3O2S
[MDL Number]

MFCD00948114
[MOL File]

179420-17-8.mol
[Molecular Weight]

393.5
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: ≥10mg/mL
[form ]

powder
[color ]

white to tan
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

CJ-13610 may be used to study 5-lipoxygenase-mediated cell signaling.
[Biochem/physiol Actions]

CJ-13610 inhibits the biosynthesis of leukotriene B4 and regulates the IL-6 mRNA expression in macrophages. It reduces fibrosis and necroinflammation of liver in carbon tetrachloride-treated mice.
[storage]

Store at -20°C
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