| Identification | Back Directory | [Name]
Centrinone-B | [CAS]
1798871-31-4 | [Synonyms]
LCR-323
Centrinone-B
Centrinone B,CentrinoneB
2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine
4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)- | [Molecular Formula]
C27H27F2N7O5S2 | [MDL Number]
MFCD29472297 | [MOL File]
1798871-31-4.mol | [Molecular Weight]
631.67 |
| Chemical Properties | Back Directory | [Boiling point ]
904.9±75.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 8.5 mg/mL (13.46 mM) | [form ]
Solid | [pka]
13.68±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Centrinone-B is a high affinity and selective PLK4 inhibitor. It depletes centriole and centrosome levels in vitro and induces cell cycle arrest in normal human cell lines in a p53-dependent manner. | [storage]
Store at -20°C |
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Musechem
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+1-800-259-7612 |
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www.musechem.com |
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BOC Sciences
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https://www.bocsci.com |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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