Identification | Back Directory | [Name]
(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline | [CAS]
180272-45-1 | [Synonyms]
Solifenacin Impurity 2 Solifenacin Impurity 42 (S)-quinuclidin-3-yl acetate Solifenacin Related Compound 9 Solifenacin Succinate interMediate G (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline (R)-1-Phenyl-1,2,3,4-tetrhydroisoquinoline (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline (R)-1,2,3,4-Tetrahydro-1-phenylisoquinoline (1R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline (1R)-1,2,3,4-Tetrahydro-1-phenyl-isoquinoline (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline(W.S) Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-, (1R)- (R)-1,2,3,4-Tetrahydro-1-phenylisoquinoline,99%e.e. TIANFU-CHEM (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Solifenacin impurity 10/Solifenacin R Isomer/(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline | [Molecular Formula]
C15H15N | [MOL File]
180272-45-1.mol | [Molecular Weight]
209.286 |
Hazard Information | Back Directory | [Uses]
(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the counterpart to (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, the latter enantiomer being a key intermediate in the preparation of Solifenacin (S676700), an antimuscarinic agent. Since (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is produced as a by-product, it has been suggested that it should be recycled in order to obtain the S enantiomer on a larger scale. (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is also used as a reagent to prepare quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives, compounds that act as muscarinic receptor antagonists. |
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