| Identification | Back Directory | [Name]
Fmoc-N-methyl-N-amido-PEG2-acid | [CAS]
1807518-77-9 | [Synonyms]
Fmoc-NMe-PEG2-acid
Fmoc-N-methyl-PEG3-CH2CH2COOH
Fmoc-N-methyl-N-amido-PEG2-acid
Fmoc-N-methyl-N-amido-PEG2-COOH
5,8,11-Trioxa-2-azatetradecanedioic acid, 2-methyl-, 1-(9H-fluoren-9-ylmethyl) ester | [Molecular Formula]
C25H31NO7 | [MDL Number]
MFCD29918264 | [MOL File]
1807518-77-9.mol | [Molecular Weight]
457.52 |
| Chemical Properties | Back Directory | [Boiling point ]
630.5±55.0 °C(Predicted) | [density ]
1.218±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [pka]
4.28±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Fmoc-N-methyl-N-amido-PEG2-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. |
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