| Identification | Back Directory | [Name]
Hydroxy-PEG3-PFP ester | [CAS]
1807537-40-1 | [Synonyms]
Hydroxy-PEG3-PFP ester
Hydroxy-PEG3-C2-PFP ester | [Molecular Formula]
C15H17F5O6 | [MDL Number]
MFCD26793756 | [MOL File]
1807537-40-1.mol | [Molecular Weight]
388.28 |
| Hazard Information | Back Directory | [Biological Activity]
Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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| Company Name: |
A.J Chemicals
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91-9810153283 |
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www.ajchemicals.com |
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