Identification | Back Directory | [Name]
(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide | [CAS]
1809784-29-9 | [Synonyms]
DTP3 DTP3 inhibitor D-Phenylalaninamide, N-acetyl-D-tyrosyl-D-arginyl- cancer,DTP 3,inhibit,Inhibitor,Janus kinase,DNA/RNA Synthesis,NF-κB,DTP-3,tumor,GADD45β,DTP3,JAK (R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide (R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide USP/EP/BP | [Molecular Formula]
C26H35N7O5 | [MDL Number]
MFCD28348368 | [MOL File]
1809784-29-9.mol | [Molecular Weight]
525.6 |
Chemical Properties | Back Directory | [density ]
1.35±0.1 g/cm3(Predicted) | [solubility ]
DMSO:100.0(Max Conc. mg/mL);190.26(Max Conc. mM) Ethanol:100.0(Max Conc. mg/mL);190.26(Max Conc. mM) Water:100.0(Max Conc. mg/mL);190.26(Max Conc. mM) | [form ]
Solid | [pka]
9.83±0.15(Predicted) | [color ]
White to off-white | [CAS DataBase Reference]
1809784-29-9 |
Hazard Information | Back Directory | [Uses]
DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits the cancer-selective NF-κB survival pathway. It specifically kills cells and induces apoptosis in MM cells without being toxic to normal cells.m |
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