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1824544-52-6

1824544-52-6 Structure

1824544-52-6 Structure
IdentificationBack Directory
[Name]

3-keto Sphinganine (d6:0) (hydrochloride)
[CAS]

1824544-52-6
[Synonyms]

3-keto Sphinganine (d6:0) (hydrochloride)
[Molecular Formula]

C6H14ClNO2
[MDL Number]

MFCD24491777
[MOL File]

1824544-52-6.mol
[Molecular Weight]

167.63
Chemical PropertiesBack Directory
[form ]

A solid
Hazard InformationBack Directory
[Description]

3-keto Sphinganine (d6:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0) . 3-keto Sphinganine (d18:0) is a lyso-sphingolipid formed by the condensation of L-serine and palmitoyl-CoA by serine palmitoyl transferase (SPT). Vitamin K deficiency inactivates SPT resulting in a decrease in the production of 3-keto sphinganine and other sphingolipids.1
[References]

1. Batheja, A.D., Uhlinger, D.J., Carton, J.M., et al. Characterization of serine palmitoyltransferase in normal human tissues J. Histochem. Cytochem. 51(5),687-696(2003).
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