ChemicalBook--->CAS DataBase List--->184582-91-0

184582-91-0

184582-91-0 Structure

184582-91-0 Structure
IdentificationBack Directory
[Name]

DMPAC-Chol
[CAS]

184582-91-0
[Synonyms]

DMPAC-Chol
DMPAC Chol,DMPACChol
[Molecular Formula]

C33H58N2O2
[MOL File]

184582-91-0.mol
[Molecular Weight]

514.84
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF:10.0(Max Conc. mg/mL);19.42(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);19.42(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.27(Max Conc. mM)
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 μg/ml.
[storage]

Store at -20°C
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