ChemicalBook--->CAS DataBase List--->1852-38-6

1852-38-6

1852-38-6 Structure

1852-38-6 Structure
IdentificationBack Directory
[Name]

PREGNENOLONE SULFATE SODIUM SALT
[CAS]

1852-38-6
[Synonyms]

Pregnenolone 3-Sulfate
PREGNENOLONE SULFATE SODIUM
SodiuM Pregnenolone-d4 Sulfate
5-Pregnen-3β-ol-20-one sulfate
Pregnenolone sulphate Na+ salt
PREGNENOLONE SULFATE SODIUM SALT
PREGNENOLONE SULPHATE, SODIUM SALT
Pregnenolone-3-sulfate SodiuM Salt
3-Hydroxypregn-5-en-20-one sulfate
Pregnenolone monosulfate sodium salt
3β-Hydroxy-5-pregnen-20-one 3-sulfate
5-pregnen-3B-ol-20-one sulfate sodium
5-PREGNEN-3BETA-OL-20-ONE3-SULFATE SODIUM
5-PREGNEN-3B-OL-20-ONE SULFATE SODIUM SALT
5-PREGNEN-3BETA-OL-20-ONE SULFATE SODIUM SALT
3-HYDROXYPREGN-5-EN-20-ONE SULFATE SODIUM SALT
(3β)-3-(Sulfooxy)-pregn-5-en-20-one sodium salt
5-Pregnen-3-beta-ol-2o-one sulphate,sodium salt
5-PREGNEN-3-BETA-OL-20-ONE SULPHATE, SODIUM SALT
3B-HYDROXY-5-PREGNEN-20-ONE 3-SULFATE SODIUM SALT
3β-Hydroxy-5-pregnen-20-one monosulfate sodium salt
3-BETA-HYDROXY-5-PREGNEN-20-ONE 3-SULPHATE, SODIUM SALT
PREGNENOLONE SULFATE SODIUM SALT 5-PREGN EN-3B-OL-20-ON
3β-Hydroxy-5-pregnen-20-one 3-sulfate, 3-Hydroxypregn-5-en-20-one sulfate, 5-Pregnen-3β-ol-20-one sulfate
[Molecular Formula]

C21H31NaO5S
[MDL Number]

MFCD00056177
[MOL File]

1852-38-6.mol
[Molecular Weight]

418.52
Chemical PropertiesBack Directory
[Melting point ]

192 °C(lit.)
[storage temp. ]

Store at -20°C
[solubility ]

methanol and water: 1.93 mg/mL
[form ]

A crystalline solid
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

Pregnenolone sulfate is a metabolite of the natural steroid hormone pregnenolone . Pregnenolone sulfate modulates NMDA receptor responses to exogenously applied glutamate and stimulates transient receptor potential melastatin 3 (TRPM3).
[Uses]

Pregnenolone sulfate sodium salt has been used as sigma-1 receptor (σ1R) agonist. It has also been used in the stimulation and as a ligand for transient receptor potential melastatin-3 (TRPM3).
[Uses]

Pregnenolone Sulfate Sodium Salt, is a metabolite of Pregnenolone (P712200). It is also a neuroactive steroid, a potent and efficacious modulators of the GABAA receptor.
[Biochem/physiol Actions]

Pregnenolone sulfate is a neurosteroid and a neuromodulator. It is involved in the stimulation of N-methyl-D-aspartate receptor (NMDA), γ-Aminobutyric acid type A (GABAA?) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA-kainate). It activates transient receptor potential melastatin (TRPM3) which is a calcium-permeable ion channel. It improves schizophrenia and behavioral anomalies by modulating NMDA mediated Ser/Thr kinase - glycogen synthase kinase 3 β (AKT/GSK3β) signaling pathway.
[storage]

Store at +4°C
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