| Identification | Back Directory | [Name]
DU-14 | [CAS]
186303-55-9 | [Synonyms]
DU-14
TETRADECANAMIDE, N-[2-[4-[(AMINOSULFONYL)OXY]PHENYL]ETHYL]- | [Molecular Formula]
C22H38N2O4S | [MDL Number]
MFCD19381840 | [MOL File]
186303-55-9.mol | [Molecular Weight]
426.61 |
| Chemical Properties | Back Directory | [storage temp. ]
RT | [solubility ]
Soluble in DMSO (up to 25 mg/ml). | [form ]
solid | [color ]
Off-white | [Stability:]
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| Hazard Information | Back Directory | [Description]
DU-14 (186303-55-9) inhibits steroid sulfatase (IC50=ca. 60 nM). Enhances learning and spatial memory in rats.1 Inhibits proliferation of human MCF-7 breast cancer cells.2 | [References]
1) Johnson et al. (2000), The effect of steroid sulfatase inhibition on learning and spatial memory; Brain Res., 865 286
2) Selcer et al. (1997), Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N-alkanoyl tyramines; Cancer Res., 57 702 |
|
|