| Identification | Back Directory | [Name]
Genistein-D4 (4-Hydroxyphenyl-2,3,5,6-D4) | [CAS]
187960-08-3 | [Synonyms]
GeniVida-d4
Bonistein-d4
Genisteol-d4
Baichanin A-d4
4',5,7-Trihydroxyisoflavone-d4
Genistein-2',3',5',6'-d4 (Major)
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d4
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl-2,3,5,6-d4)- | [Molecular Formula]
C15H6D4O5 | [MOL File]
187960-08-3.mol | [Molecular Weight]
274.263 |
| Chemical Properties | Back Directory | [Melting point ]
290-292°C (dec.) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Light Yellow to Yellow | [Stability:]
Light Sensitive - Protect From Light |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol | [storage]
Store at -20°C |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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