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1883548-86-4

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1883548-86-4 Structure

1883548-86-4 Structure
IdentificationBack Directory
[Name]

PF 06260933 dihydrochloride
[CAS]

1883548-86-4
[Synonyms]

PF-06260933 HCl
PF-06260933 2HCl
PF 6260933 dihydrochloride
PF 06260933 dihydrochloride
[Molecular Formula]

C16H14Cl2N4
[MDL Number]

MFCD29049536
[MOL File]

1883548-86-4.mol
[Molecular Weight]

333.22
Chemical PropertiesBack Directory
[solubility ]

Soluble to 100 mM in water and to 20 mM in DMSO
Hazard InformationBack Directory
[Description]

PF-06260933 dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). PF-06260933 dihydrochloride has been shown to improves fasting hyperglycemia in mice. (
[storage]

Desiccate at RT
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