ChemicalBook--->CAS DataBase List--->189302-40-7

189302-40-7

189302-40-7 Structure

189302-40-7 Structure
IdentificationBack Directory
[Name]

N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
[CAS]

189302-40-7
[Synonyms]

nor-NOHA diacetate
NOR-NOHA, 2CH3CO2H
N-w-Hydroxy-L-norarginine
N-o-Hydroxy-L-norarginine
N---Hydroxy-nor-L-arginine
N-omega-Hydroxy-L-norarginine
N-w-Hydroxy-L-norarginine diacetate salt
N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
(S,E)-2-aMino-4-(2-hydroxyguanidino)butanoic acid
N-w-Hydroxy-L-norarginine diacetate salt≥ 97% (TLC)
L-2-Amino-{4-(2'-hydroxyguanidino)butyric acid diacetate
L-2-AMINO-(4-(2'-HYDROXYGUANIDINO)BUTYRIC ACID), 2CH3CO2H
Butanoic acid, 2-amino-4-[[(hydroxyamino)iminomethyl]amino]-, (2S)-
L-2-AMino-4-(2'-hydroxyguanidino)-butyric acid, nor-NOHA, H-Nar(OH)-OH
[Molecular Formula]

C5H12N4O3
[MDL Number]

MFCD01318777
[MOL File]

189302-40-7.mol
[Molecular Weight]

176.17
Chemical PropertiesBack Directory
[storage temp. ]

Store at 0°C
[form ]

White to slightly yellowish powder.
Hazard InformationBack Directory
[Chemical Properties]

Off-white powder
[Definition]

ChEBI: Nomega-hydroxy-nor-l-arginine is a L-alpha-amino acid.
[General Description]

A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 μM) and mouse macrophages (IC50 = 50 μM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.
[Biochem/physiol Actions]

Primary Targetarginase from rat liver
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