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1897379-34-8

1897379-34-8 Structure

1897379-34-8 Structure
IdentificationBack Directory
[Name]

(2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride
[CAS]

1897379-34-8
[Synonyms]

SLM6031434 HCl
SLM6031434 (hydrochloride)
SLM-6031434 HCl,SLM6031434 HCl
(S)-2-(3-(4-(Octyloxy)-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboximidamide hydrochloride
(2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride
[Molecular Formula]

C22H31ClF3N5O2
[MDL Number]

MFCD31689247
[MOL File]

1897379-34-8.mol
[Molecular Weight]

489.97
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 5 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Uses]

SLM 6031434 Hydrochloride is a Sphk2 inhibitor (Ki = 0.4 μM for mouse Sphk2). Exhibts some selectivity for Sphk2 over Sphk1 (Ki > 20 μM). Decreases levels of sphingosine-1-phosphate (S1P) in U937 cells in vitro and increases blood levels of S1P in wild-type mice.
[storage]

Store at -20°C
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