| Identification | Back Directory | [Name]
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- | [CAS]
1903742-34-6 | [Synonyms]
JYN42346
Complement factor D-IN-2
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)- | [Molecular Formula]
C27H24BrN7O3 | [MDL Number]
MFCD34471171 | [MOL File]
1903742-34-6.mol | [Molecular Weight]
574.43 |
| Chemical Properties | Back Directory | [Boiling point ]
849.1±65.0 °C(Predicted) | [density ]
1.67±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
11.72±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases[1].
Complement factor D-IN-2 reduces the excessive activation of complement factor D[1]. | [References]
[1]. GADHACHANDA VR, et, al. Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders. WO2015130838A1. |
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| Company Name: |
DC Chemicals
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| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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