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1914989-80-2

1914989-80-2 Structure

1914989-80-2 Structure
IdentificationBack Directory
[Name]

3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-
[CAS]

1914989-80-2
[Synonyms]

Aβ42-IN-2
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-
[Molecular Formula]

C24H26N6O2
[MDL Number]

MFCD32857167
[MOL File]

1914989-80-2.mol
[Molecular Weight]

430.5
Chemical PropertiesBack Directory
[storage temp. ]

4°C, stored under nitrogen
[solubility ]

DMSO : 20 mg/mL (46.46 mM; Need ultrasonic)
Spectrum DetailBack Directory
[Spectrum Detail]

3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-(1914989-80-2)1HNMR
Hazard InformationBack Directory
[Biological Activity]

Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for αβ42. Aβ42-IN-2 can be used for the research of Alzheimer’s disease[1].
[References]

[1]. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1.
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