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192187-67-0

192187-67-0 Structure

192187-67-0 Structure
IdentificationBack Directory
[Name]

7α,27-dihydroxy-4-cholesten-3-one
[CAS]

192187-67-0
[Synonyms]

27-dihydroxy-4-cholesten-3-one
7α,27-dihydroxy-4-cholesten-3-one
(25R)-7α,26-dihydroxycholest-4-en-3-one
(7α,25R)-7,26-Dihydroxy-cholest-4-en-3-one
(7α,?25R)?-7,?26-?Dihydroxy-cholest-?4-?en-?3-?one
7Α,27-DIHYDROXY-4-CHOLESTEN-3-ONE;7Α;27-DIHYDROXY-4-CHOLESTEN-3-ONE
[Molecular Formula]

C27H44O3
[MDL Number]

MFCD22416718
[MOL File]

192187-67-0.mol
[Molecular Weight]

416.65
Chemical PropertiesBack Directory
[Boiling point ]

554.5±33.0 °C(Predicted)
[density ]

1.08±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

powder
[pka]

14.49±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

(7α,?25R)?-7,?26-?Dihydroxy-cholest-?4-?en-?3-?one is derived from (25R)-26-Hydroxy-cholest-4-en-3-one (H917940), which is an oxygenated sterol which has many important biological activities.
[Definition]

ChEBI: (25R)-7alpha,26-dihydroxycholest-4-en-3-one is an oxysterol that is cholesterol which is substituted by an oxo group at position 3 and hydroxy groups at positions 7alpha and 26. It has R-configuration at position 25. It has a role as a human metabolite. It is a 26-hydroxy steroid, a 3-oxo steroid, a 7alpha-hydroxy steroid and a cholestanoid.
[Biological Activity]

7α,27-dihydroxy-4-cholesten-3-one is a suppressor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
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