| Identification | Back Directory | [Name]
5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4- diamine | [CAS]
192314-93-5 | [Synonyms]
AR 100
iclaprim
Iclaprim Methanesulfonate
5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4- diamine
2,4-Pyrimidinediamine, 5-[(2-cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]-
5-[(2-Cyclopropyl-7,8-diMethoxy-2H-1-benzopyran-5-yl)Methyl]-2,4-pyriMidine-
diaMine
5-(2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-ylmethyl)-pyrimidine-2,4-diamine (ICLAPRIM]
5-((2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl)pyrimidine-2,4-diamine(WXG01982) | [EINECS(EC#)]
606-269-6 | [Molecular Formula]
C19H22N4O3 | [MDL Number]
MFCD09837803 | [MOL File]
192314-93-5.mol | [Molecular Weight]
354.4 |
| Chemical Properties | Back Directory | [Boiling point ]
616.7±65.0 °C(Predicted) | [density ]
1.332±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:30.0(Max Conc. mg/mL);84.65(Max Conc. mM) | [form ]
Solid | [pka]
7.07±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
14g/L at 20℃ |
| Hazard Information | Back Directory | [Uses]
Iclaprim is a novel antibacterial agent that is currently in development for the treatment of complicated skin and skin structure infections (cSSSI). | [Definition]
ChEBI: 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine is an aminopyrimidine that is 5-methylpyrimidine-2,4-diamine in which one of the hydrogens of the methyl group has been replaced by a 2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl group. It is an aminopyrimidine, a member of chromenes and a member of cyclopropanes. |
|
|