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193359-26-1

193359-26-1 Structure

193359-26-1 Structure
IdentificationBack Directory
[Name]

1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE
[CAS]

193359-26-1
[Synonyms]

184832
Co 101244
CO 101244 HYDROCHLORIDE
1-(2-(4-hydroxyphenoxy)ethyl)-4-(4-methylbenzyl)piperidin-4-ol
4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-
1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinolhydrochloride
1-[2-(4-HYDROXYPHENOXY)ETHYL]-4-[(4-METHYLPHENYL)METHYL]-4-PIPERIDINOL MONOHYDROCHLORIDE
[Molecular Formula]

C21H27NO3
[MDL Number]

MFCD08703124
[MOL File]

193359-26-1.mol
[Molecular Weight]

341.44
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
Hazard InformationBack Directory
[Uses]

Co 101244 is a highly selective N-methyl-D-aspartate NR2B subtype antagonist.
[Biological Activity]

Novel, potent and selective antagonist of NR2B-containing NMDA receptors (IC 50 values are 0.043, > 100 and > 100 μ M for NR1A/2B, NR1A/2A and NR1A/2C subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro .
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