| Identification | Back Directory | [Name]
Oregon Green 488 carboxylic acid | [CAS]
195136-52-8 | [Synonyms]
OG 488, acid
Oregon Green 488 carboxylic acid
Oregon Green 488 carboxylic acid 5-isomer
2',7'-difluorofluorescein-5-carboxylic acid
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 2',7'-difluoro-3',6'-dihydroxy-3-oxo- | [Molecular Formula]
C21H10F2O7 | [MOL File]
195136-52-8.mol | [Molecular Weight]
412.3 |
| Chemical Properties | Back Directory | [Melting point ]
>250°C | [solubility ]
Solubility Insoluble in water; soluble in N,N-dimethylformamide | [form ]
Solid | [pka]
4.7(at 25℃) | [color ]
Orange powder | [PH Range]
Weak green N uorescence (4.2) to strong green N uorescence (5.7) | [λmax]
478nm, 492nm | [Biological Applications]
Analysizing single cells; detecting intracellular analytes, undetectable analytes; as marker for Arginine8-vasotocin (AVT) targetneurons; measuringphagosomalpH; monitoring melting of duplex DNA; temperature gradient focusing; studying actin dynamics in plant cells | [Major Application]
Sensors, methods of determining human blood-relationship, method for purifying actin in plant cells, phagosomal pH determination |
| Hazard Information | Back Directory | [Uses]
Oregon Green 488 Carboxylic Acid, is a novel Fluorinated Fluorescein agent that can be used in biological experiments in which fluorescein is covalently attached to materials such as peptides, proteins (especially antibodies), nucleotides, oligonucleotides, drugs, hormones, lipids, and other biomolecules. | [Definition]
ChEBI: Oregon green 488 is a xanthene dye having two fluoro substituents at the 2- and 7-positions and a 2,4-dicarboxyphenyl group at the 9-position. It has a role as a fluorochrome and an epitope. It is functionally related to a fluorescein (acid form). |
|
|