ChemicalBook--->CAS DataBase List--->195209-04-2

195209-04-2

195209-04-2 Structure

195209-04-2 Structure
IdentificationBack Directory
[Name]

ACPT-II
[CAS]

195209-04-2
[Synonyms]

ACPT-II
ACPTII,ACPT II
(1R,3R,4S)-1-AMINOCYCLOPENTANE-1,3,4-TRICARBOXYLIC ACID
4-AMINO-1ALPHA,2ALPHA,4BETA-CYCLOPENTANETRICARBOXYLIC ACID
1,2,4-Cyclopentanetricarboxylic acid, 4-amino-, (1α,2α,4α)-
[Molecular Formula]

C8H11NO6
[MDL Number]

MFCD08705256
[MOL File]

195209-04-2.mol
[Molecular Weight]

217.176
Chemical PropertiesBack Directory
[Boiling point ]

440.4±45.0 °C(Predicted)
[density ]

1.651±0.06 g/cm3(Predicted)
[storage temp. ]

Desiccate at -20°C
[solubility ]

DMF: 5 mg/ml; DMSO: 0.25 mg/ml; PBS pH 7.2: 10 mg/ml
[form ]

A crystalline solid
[pka]

1.85±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

ACPT-II is a metabotropic glutamate receptor agonist, which exerts neuroprotective effects against kainate-induced excitotoxicity in primary neuronal cell and the dorsal hippocampus of rats.
[Biological Activity]

Competitive metabotropic receptor antagonist (K b values are 115, 88 and 77 μ M at mGlu 1a , mGlu 2 and mGlu 4a respectively).
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