Identification | Back Directory | [Name]
(RS)-3,5-DHPG | [CAS]
19641-83-9 | [Synonyms]
(RS)-3 5-DHPG 2-amino-2-(3 (RS)-3,5-DHPG TOC(RS)-3-5DHPG (RS)-3,5-DHPG USP/EP/BP 5-Dihydroxyphenylglycine 5-dihydroxyphenyl)acetic acid 2-ethylhexanoate,samarium(3+) ((+/-)-3,5-DHPG Hydrochloride (RS)-3,5-DIHYDROXYPHENYLGLYCINE DL-ALPHA-(3,5-DIHYDROXYPHENYL)GLYCINE | [Molecular Formula]
C8H9NO4 | [MDL Number]
MFCD00272595 | [MOL File]
19641-83-9.mol | [Molecular Weight]
183.16 |
Chemical Properties | Back Directory | [Melting point ]
>181°C (Dec.) | [storage temp. ]
Desiccate at -20°C | [solubility ]
Acetonitrile (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Uses]
(RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson''s disease. | [Biological Activity]
Selective group I metabotropic glutamate receptor agonist which activates both mGlu 1 and mGlu 5 . Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D. |
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