ChemicalBook--->CAS DataBase List--->196603-47-1

196603-47-1

196603-47-1 Structure

196603-47-1 Structure
IdentificationBack Directory
[Name]

ZM 306416 hydrochloride
[CAS]

196603-47-1
[Synonyms]

ZM-306416 HCI
[Molecular Formula]

C16H14Cl2FN3O2
[MDL Number]

MFCD08703133
[MOL File]

196603-47-1.mol
[Molecular Weight]

370.21
Chemical PropertiesBack Directory
[storage temp. ]

RT
[solubility ]

Soluble in DMSO (up to 5 mg/ml).
[form ]

solid
[color ]

White
[Stability:]

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Hazard InformationBack Directory
[Description]

ZM-306416 (196603-47-1) is a VEGF receptor tyrosine kinase inhibitor with selectivity over FGFR-1 (KDR IC50 = 100 nM; FLT IC50 = 2 μM).
[Uses]

ZM 306416 Hydrochloride, is an inhibitor of tyrosine kinase RTK signaling pathway involved in anti-cancer agents. Anti-tumor, anti-metastatic agent.
[storage]

Store at -20°C
[References]

1) Hennequin et al. (1999) Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. J. Med. Chem. 42 5369
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