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199522-35-5

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199522-35-5 Structure

199522-35-5 Structure
IdentificationBack Directory
[Name]

NNC 26-9100
[CAS]

199522-35-5
[Synonyms]

NNC 26-9100
1-[3-[N-(5-Bromopyridin-2-yl)-N-(3,4-dichlorobenzyl)amino]propyl]-3-[3-(1H-imidazol-4-yl)propyl]thiourea
Thiourea, N-[3-[(5-bromo-2-pyridinyl)[(3,4-dichlorophenyl)methyl]amino]propyl]-N'-[3-(1H-imidazol-5-yl)propyl]-
[Molecular Formula]

C22H25BrCl2N6S
[MDL Number]

MFCD09038560
[MOL File]

199522-35-5.mol
[Molecular Weight]

556.35
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

Soluble to 50 mM in DMSO and to 50 mM in ethanol
[form ]

Powder
Hazard InformationBack Directory
[Uses]

NNC 26-9100 is a Somatostatin (SRIF, somatotropin release inhibiting factor) receptor.
[Definition]

ChEBI: 1-[3-[(5-bromo-2-pyridinyl)-[(3,4-dichlorophenyl)methyl]amino]propyl]-3-[3-(1H-imidazol-5-yl)propyl]thiourea is an aminopyridine.
[Biological Activity]

Somatostatin sst 4 receptor agonist that displays > 100-fold selectivity over sst 2 receptors (K i values are 6 and 621 nM for sst 4 and sst 2 receptors respectively). Potently inhibits forskolin-induced cAMP accumulation (EC 50 = 26 nM).
[storage]

Store at -20°C
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