ChemicalBook--->CAS DataBase List--->199934-16-2

199934-16-2

199934-16-2 Structure

199934-16-2 Structure
IdentificationBack Directory
[Name]

6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE
[CAS]

199934-16-2
[Synonyms]

UCL 1684
UCL-1684 Br
UCL 1684 dibromide
6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,
6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,13-diiumdibromide
6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE
[Molecular Formula]

C38H30F6N4O4
[MDL Number]

MFCD06798362
[MOL File]

199934-16-2.mol
[Molecular Weight]

720.66
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at RT
[solubility ]

DMSO: 10 mg/mL
[form ]

Powder
[color ]

white to off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

UCL 1684 is a highly potent and selective, nonpeptidic blocker of the Apamin-sensitive Ca2+-activated K+ channel of which inhibition potentially terminates and protects against atrial fibrillation.
[Biological Activity]

Highly potent, non-peptidic blocker of the apamin-sensitive Ca 2+ -activated K + channel (SK Ca ) (IC 50 = 3 nM in rat sympathetic neurons). Blocks hSK1 and rSK2 channels expressed in HEK 293 cells with IC 50 values of 762 and 364 pM respectively.
[storage]

Desiccate at RT
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