| Identification | Back Directory | [Name]
E3 ligase Ligand-Linker Conjugates 5 Free Base | [CAS]
2010159-56-3 | [Synonyms]
VH032-PEG3-NH2
(S,R,S)-AHPC-PEG3-NH2
PROTACs Related Compound 7
VHL Ligand-Linker Conjugates 1
(S, R, S)-AHPC-PEG3-amine hydrochloride salt
E3 ligase Ligand-Linker Conjugates 5 Free Base
(S,R,S)-AHPC-PEG3-NH2 （E3 ligase Ligand-Linker Conjugates 5）
L-Prolinamide, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | [Molecular Formula]
C30H45N5O7S | [MDL Number]
MFCD31727698 | [MOL File]
2010159-56-3.mol | [Molecular Weight]
619.77 |
| Chemical Properties | Back Directory | [Boiling point ]
879.2±65.0 °C(Predicted) | [density ]
1.238±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [form ]
Solid | [pka]
13.54±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
(S, R, S)-AHPC-PEG3-amine hydrochloride salt is comprised of VHL Ligand coupled to an amine via a PEG3 linker. The 1 VHL Ligand 1 is a synthetic compound used in PROTAC research based on E3 ligase ligand. NH2 group is reactive with carboxylic acids in the presence of coupling reagent such as EDC , or directly with NHS esters, to form a stable amide bond. |
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