| Identification | Back Directory | [Name]
Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) | [CAS]
20324-87-2 | [Synonyms]
AMI-1;AMI 1;AMI1
AMI-1 disodium salt
AMI-1 - AMI-1 sodium salt
J acid urea,disodiuM salt 70%
Disodium 6,6'-ureylenebis[1-naphthol-3-sulfonate]
Sodium 6,6'-(1,3-ureylene) bis(1-naphthol-3-sulfonate)
SODIUM 6,6'-(1,3-UREYLENE) BIS(1,1'-NAPHTHOL)-3,3'-SULFONATE
Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)
7,7'-(carbonyldiimino)bis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt
4-hydroxy-7-[(5-hydroxy-7-sulfonatonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate
disodium 4-hydroxy-7-[(5-hydroxy-7-sulfonato-2-naphthyl)carbamoylamino]naphthalene-2-sulfonate
disodium 4-hydroxy-7-[(5-hydroxy-7-sulfonatonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate
disodium 4-hydroxy-7-[(5-hydroxy-7-sulfonato-naphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate | [EINECS(EC#)]
243-735-4 | [Molecular Formula]
C21H14N2Na2O9S2 | [MDL Number]
MFCD00068249 | [MOL File]
20324-87-2.mol | [Molecular Weight]
548.45 |
| Hazard Information | Back Directory | [Uses]
AMI-1 is a Histone Methyltransferase (HMT) inhibitor. | [Biological Activity]
potent, cell permeable and specific protein arginine n-methyltransferase 1 (prmt1) inhibitor (ic50 = 8, 8 μm), does not compete for the adomet (s-adenosyl-l-methionine, sam) binding site, blocks peptide substrate binding, hiv-1 rt polymerase inhibitor (ic50 = 5, 0 μm). |
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