| Identification | Back Directory | [Name]
1,2,9,10-TETRACHLORODECANE | [CAS]
205646-11-3 | [Synonyms]
CP-2
1,2,9,10-TETRACHLORODECANE
Decane, 1,2,9,10-tetrachloro- | [Molecular Formula]
C10H18Cl4 | [MDL Number]
MFCD01632392 | [MOL File]
205646-11-3.mol | [Molecular Weight]
280.06 |
| Hazard Information | Back Directory | [Biological Activity]
1,2,9,10-Tetrachlorodecane is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50s of 42 nM and 29 nM for KDM4A and KDM4C, respectively. | [in vitro]
1,2,9,10-Tetrachlorodecane specifically binds to the KDM4A substrate binding pocket. It binds to the KDM4A active site competitively with histone substrates. | [target]
| Target | Value | KDM4C
(Cell-free assay) | 29 nM | KDM4A
(Cell-free assay) | 42 nM |
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| Company Name: |
Chiron AS
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+47 73 87 4490 |
| Website: |
www.chiron.no |
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