| Identification | Back Directory | [Name]
2'-O,4'-C-Methylenecytidine | [CAS]
206055-69-8 | [Synonyms]
2'-O,4'-C-Methylenecytidine
Cytidine, 2'-O,4'-C-methylene-
2’-O,4’-C-Methylenecytidine, LNA-C | [Molecular Formula]
C10H13N3O5 | [MDL Number]
MFCD28342628 | [MOL File]
206055-69-8.mol | [Molecular Weight]
255.23 |
| Hazard Information | Back Directory | [Biological Activity]
2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2]. | [References]
[1]. bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes [2]. Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04. |
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