| Identification | Back Directory | [Name]
5'-INOSINIC ACID DISODIUM SALT HYDRATE | [CAS]
20813-76-7 | [Synonyms]
5'-IMP-Na2
5'-IMP-NA2 OCTAHYDRATE
IMP DISODIUM SALT HYDRATE
methyl phosphate octahydrate
5-inosine disodium monophosphate
-INOSINIC ACID DISODIUM SALT HYDRATE
5'-INOSINIC ACID DISODIUM SALT HYDRATE
-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)
5'-Inosinic acid disodium salt octahydrate
Inosine-5'-monophosphate (sodium salt hydrate)
INOSINE-5'-MONOPHOSPHATESODIUMSALT,OCTAHYDRATE
5'-INOSINIC ACID DISODIUM SALT HYDRATE USP/EP/BP
INOSINE 5'-MONOPHOSPHATE DISODIUM SALT N-HYDRATE
INOSINE-5'-MONOPHOSPHATE DISODIUM SALT OCTAHYDRATE
Sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl phosphate octahydrate | [EINECS(EC#)]
225-146-4 | [Molecular Formula]
C10H13N4Na2O9P | [MDL Number]
MFCD00150372 | [MOL File]
20813-76-7.mol | [Molecular Weight]
410.18 |
| Chemical Properties | Back Directory | [Melting point ]
175 °C
| [storage temp. ]
0-6°C | [solubility ]
Aqueous Acid (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
Inosine-5''-monophosphate (IMP) is a substrate of IMP dehydrogenase (IMPDH), a NAD+-dependent enzyme that generates xanthosine monophosphate. This is a rate-limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. Inhibitors of IMPDH, including ribavirin (Item No. 16757) and mycophenolate mofetil (Item No. 13988), have potential applications as antiviral and anti-cancer drugs.1,2,3 5-Ribonucleosides, including IMP, are also involved in potentiating the umami taste sensation.4 | [Uses]
Inosine-5''-monophosphate Sodium Salt Hydrate can be used for synthesis of fresh sauce for casserole. It is a sodium salt hydrate form of Inosine 5''-monophosphate (I665003), which can be used in combination with an immune checkpoint inhibitor for cancer immunotherapy. | [storage]
Store at -20°C |
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