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208848-19-5

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208848-19-5 Structure

208848-19-5 Structure
IdentificationBack Directory
[Name]

FRESELESTAT
[CAS]

208848-19-5
[Synonyms]

ONO6818
ONO-6818
ONO 6818
Freselesat
ONO-PO-736
FRESELESTAT
5-Amino-N-[1-[[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]carbonyl]-2-methylpropyl]-6-oxo-2-phenyl-1(6H)-pyrimidineacetamide
1(6H)-PyriMidineacetaMide,5-aMino-N-[1-[[5-(1,1-diMethylethyl)-1,3,4-oxadiazol-2-yl]carbonyl]-2-Methylpropyl]-6-oxo-2-phenyl-
[Molecular Formula]

C23H28N6O4
[MDL Number]

MFCD09837826
[MOL File]

208848-19-5.mol
[Molecular Weight]

452.51
Chemical PropertiesBack Directory
[Melting point ]

151-153oC
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

12.43±0.46(Predicted)
[color ]

Off-White to Pale Yellow
Hazard InformationBack Directory
[Uses]

Freselestat is a highly potent nonpeptidic orally active inhibitor of human neutrophil elastase (HNE) and can be used as treatment for neutrophil-predominant inflammatory lung diseases.
[storage]

Store at -20°C
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