| Identification | Back Directory | [Name]
Thalidomide-NH-C6-NH2 TFA | [CAS]
2093386-51-5 | [Synonyms]
Thalidomide-NH-C6-NH2 TFA
Pomalidomide Related Compound 11 Triflate
4-((6-Aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate | [Molecular Formula]
C21H25F3N4O6 | [MDL Number]
MFCD32690101 | [MOL File]
2093386-51-5.mol | [Molecular Weight]
486.45 |
| Hazard Information | Back Directory | [Biological Activity]
Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | [References]
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. |
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