Identification | Back Directory | [Name]
1-O-HEXADECYL-(7,7,8,8-D4)-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE | [CAS]
211106-54-6 | [Synonyms]
PAF C-16-D4 HVAUUPRFYPCOCA-VGOTWLLUSA-N 1-O-HEXADECYL-(7,7,8,8-D4)-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE | [Molecular Formula]
C26H50D4NO7P | [MDL Number]
MFCD00084830 | [MOL File]
211106-54-6.mol | [Molecular Weight]
527.71 |
Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS pH 7.2: 25 mg/ml | [form ]
Liquid | [color ]
Colorless to light yellow | [Water Solubility ]
Water: 30 mg/ml |
Hazard Information | Back Directory | [Description]
PAF C-16-d4 contains four deuterium atoms at the 7, 7'', 8, and 8'' positions of the hexadecyl moiety. It is intended for use as an internal standard for the quantification of PAF C-16 by GC- or LC-mass spectrometry. PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and ''de novo'' pathways. It is a potent mediator of neutrophil migration, the production of reactive oxygen species, and IL-6 in human macrophages. It is a more potent mediator of platelet aggregation than PAF C-18. Pathological processes involving PAF include necrotizing enterocolitis, inflammation, asthma, and allergy. |
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