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2132990-98-6

2132990-98-6 Structure

2132990-98-6 Structure
IdentificationBack Directory
[Name]

FABP5-IN-1
[CAS]

2132990-98-6
[Synonyms]

FABP5-IN-1
[MDL Number]

MFCD34167502
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (233.82 mM; Need ultrasonic)
Hazard InformationBack Directory
[Biological Activity]

FABP5-IN-1 is a selective and high affinity fatty acid binding protein 5 (FABP5) inhibitor with a Ki value of 1.7 μM, and does not bind to both FABP3 and FABP7. FABP5-IN-1 shows potent antinociceptive effects[1]. FABP5-IN-1 (Compounds 4j; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model[1].
[storage]

Store at -20°C
[References]

[1]. Yan S, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Eur J Med Chem. 2018 Jun 25;154:233-252.
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