ChemicalBook--->CAS DataBase List--->213546-53-3

213546-53-3

213546-53-3 Structure

213546-53-3 Structure
IdentificationBack Directory
[Name]

NFκB Inhibitor
[CAS]

213546-53-3
[Synonyms]

SN50
NFkB Inhibitor
NF-KAPPA-B SN50
NF-κB Inhibitor, SN50
NF-KAPPAB INHIBITOR SN50
AAVALLPAVLLALLAPVQRKRQKLMP
NF-κB Inhibitor, SN50, >=97%
NUCLEAR FACTOR NF-B INHIBITOR SN50
NUCLEAR FACTOR NF-KAPPA-B INHIBITOR SN50
NF-KAPPA-B SN50, CELL-PERMEABLE INHIBITOR PEPTIDE
NF-KAPPAB SN50, CELL-PERMEABLE INHIBITORY PEPTIDE
FGF-4 PRECURSOR (7-22) (HUMAN)-EBP-1 (359-368) (HUMAN)
HST-1 PRECURSOR (7-22) (HUMAN)-DNA-BINDING FACTOR KBF1 (359-368) (HUMAN)
FIBROBLAST GROWTH FACTOR-4 PRECURSOR (7-22) (HUMAN)-NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT (359-368) (HUMAN)
H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH
FGF-4 Precursor (7-22) (huMan)-EBP-1 (359-368) (huMan), HST-1 Precursor (7-22) (huMan)-DNA-Binding Factor KBF1 (359-368) (huMan), Fibroblast Growth Factor-4 Precursor (7-22) (huMan)-Nuclear Factor NF-ΚB p105 Subunit (359-368) (huMan) TFA
L-Proline, L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-valyl-L-glutaminyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-lysyl-L-leucyl-L-methionyl-
[Molecular Formula]

C129H230N36O29S
[MDL Number]

MFCD01076531
[MOL File]

213546-53-3.mol
[Molecular Weight]

2781.5
Chemical PropertiesBack Directory
[density ]

1.36±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

film
[color ]

colorless
Hazard InformationBack Directory
[Uses]

NFkappaB Inhibitor is inhibits translocation of the NFκB active complex into the nucleus.
[Biochem/physiol Actions]

SN50 is an NF-κB cell permeable inhibitory peptide. The SN50 sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NFκB p50 linked to a peptide cell-permeabilization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). SN50 Peptide inhibits translocation of the NF-κB active complex into the nucleus.
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