| Identification | Back Directory | [Name]
Maleimide-NH-PEG12-CH2CH2COOPFP Ester | [CAS]
2136296-33-6 | [Synonyms]
Mal-NH-PEG12-CH2CH2COOPFP ester
Maleimide-NH-PEG12-CH2CH2COOPFP Ester | [Molecular Formula]
C40H59F5N2O17 | [MDL Number]
MFCD34470033 | [MOL File]
2136296-33-6.mol | [Molecular Weight]
934.89 |
| Hazard Information | Back Directory | [Biological Activity]
Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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| Company Name: |
PurePEG，LLC
|
| Tel: |
1.858.408.4567 |
| Website: |
www.purepeg.com |
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