ChemicalBook--->CAS DataBase List--->21438-66-4

21438-66-4

21438-66-4 Structure

21438-66-4 Structure
IdentificationBack Directory
[Name]

GLY-PHE BETA-NAPHTHYLAMIDE
[CAS]

21438-66-4
[Synonyms]

H-Gly-Phe-bNA
H-Gly-Phe-βNA
H-GLY-PHE-BETA-NA
gly-phe B-naphthylamide
gly-phe β-naphthylamide
Gly-Phe-β-naphthylamide
GLY-PHE BETA-NAPHTHYLAMIDE
glycylphenylalanine2-naphthylamide
glycyl-L-phenylalanine 2-naphthylamide
L-Phenylalaninamide, glycyl-N-2-naphthalenyl-
(S)-N-(2-(2-Aminoacetamido)-3-phenylpropanoyl)-2-naphthamide
[Molecular Formula]

C21H21N3O2
[MDL Number]

MFCD00021597
[MOL File]

21438-66-4.mol
[Molecular Weight]

347.41
Chemical PropertiesBack Directory
[Boiling point ]

692.4±55.0 °C(Predicted)
[density ]

1.254±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Soluble in 100mg in 200µl DMSO.
[form ]

crystalline
[pka]

13.62±0.46(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Warning
[Hazard statements ]

H351
[Precautionary statements ]

P281-P201-P202-P280-P308+P313-P405-P501a
[Hazard Codes ]

Xn
[Risk Statements ]

40
[Safety Statements ]

22-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Gly-Phe beta-naphthylamide is used to accumulate inside lysosomes leading to their destruction. Studies report that Gly-Phe-β-naphthylamide significantly inhibits the activation of caspase-8, and has also been used to study recombinant cathepsin C.
[Definition]

ChEBI: An N-(2-naphthyl)carboxamide obtained by formal condensation of the carboxy group of glycyl-L-phenylalanine with the amino group of 2-naphthylamine.
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