ChemicalBook--->CAS DataBase List--->215868-31-8

215868-31-8

215868-31-8 Structure

215868-31-8 Structure
IdentificationBack Directory
[Name]

3,5-DIFLUORO-2,4-DIHYDROXYBENZALDEHYDE
[CAS]

215868-31-8
[Synonyms]

6,8-Difluoro-7-hydroxy-3-carboxycoumarin
6,8-difluoro-7-hydroxycoumarin-3-carboxylic acid
6,8-DIFLUORO-7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID
2H-1-Benzopyran-3-carboxylic acid, 6,8-difluoro-7-hydroxy-2-oxo-
[Molecular Formula]

C10H4F2O5
[MDL Number]

MFCD25541910
[MOL File]

215868-31-8.mol
[Molecular Weight]

242.13
Chemical PropertiesBack Directory
[solubility ]

Soluble in ethyl acetate
[pka]

3.7(at 22℃)
[color ]

Green powder2
[λmax]

400nm (Buffers pH10.0)
[Biological Applications]

Analyzing JAK2 gene mutation; analyzing/identifying peptides/proteins; detecting chromosomal aberration; diagnosing classical Hodgkin lymphoma (CHL) in lymph nodes; identifying/characterizing microorganisms;treating human immunodeficiency virus (HIV) infection, ocular diseases; as temperature sensors
[Major Application]

Automotive paints
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

6,8-Difluoro-7-hydroxy-2-oxo-2H-chromene-3-carboxylic Acid can be used in the study of anti-?idiotypic antibodies targeting anti-?CD19 chimeric antigen receptors derived from 4G9 scFv for accurately detecting CAR expression of engineered T cells for use in adoptive immunotherapy for cancer.
[Definition]

ChEBI: Pacific blue is a hydroxycoumarin having the hydroxy group located at position 7 and bearing two fluoro substituents at positions 6 and 8 as well as a carboxy group at position 3. A fluorescent dye of excitation wavelength 403 nm and emission wavelength 455 nm. It has a role as a fluorochrome. It is a hydroxycoumarin, an organofluorine compound and a monocarboxylic acid.
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