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2166487-23-4

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2166487-23-4 Structure

2166487-23-4 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2166487-23-4
[Synonyms]

Et-29
NRD167
Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine
ethyl (5S)-5-((1H-indol-3-yl)methyl)-8-(((benzyloxy)carbonyl)amino)-2-methyl-4,7-dioxo-14-thioxo-3,6,13,15-tetraazaoctadecan-18-oate
[Molecular Formula]

C34H46N6O6S
[MDL Number]

MFCD34593624
[MOL File]

2166487-23-4.mol
[Molecular Weight]

666.84
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C, protect from light, stored under nitrogen
Spectrum DetailBack Directory
[Spectrum Detail]

INDEX NAME NOT YET ASSIGNED(2166487-23-4)1HNMR
Hazard InformationBack Directory
[Biological Activity]

Et-29 is a potent and selective SIRT5 inhibitor (Ki=40 nM)[1].
[References]

[1]. Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017;56(47):14836-14841.
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