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2166616-74-4

2166616-74-4 Structure

2166616-74-4 Structure
IdentificationBack Directory
[Name]

(Rac)-IDO1-IN-5
[CAS]

2166616-74-4
[Synonyms]

(Rac)-IDO1-IN-5
(Rac)-IDO-1-IN-5,(Rac) IDO1 IN 5,(Rac)IDO1IN5
[Molecular Formula]

C23H25FN2O3
[MOL File]

2166616-74-4.mol
[Molecular Weight]

396.45
Chemical PropertiesBack Directory
[Boiling point ]

665.5±55.0 °C(Predicted)
[density ]

1.251±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

13.93±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].

[storage]

Store at -20°C
[References]

[1]. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).

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