| Identification | Back Directory | [Name]
Palbociclib Impurity I | [CAS]
2172256-78-7 | [Synonyms]
6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione
Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione, 6-acetyl-8-cyclopentyl-5-methyl-
6-?Acetyl-?8-?cyclopentyl-?5-?methylpyrido[2,?3-?d]?pyrimidine-?2,?7(1H,?8H)?-?dione
6-Acetyl-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity) | [Molecular Formula]
C15H17N3O3 | [MOL File]
2172256-78-7.mol | [Molecular Weight]
287.31 |
| Chemical Properties | Back Directory | [Melting point ]
>201°C (dec.) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
10.09±0.60(Predicted) | [color ]
Light Beige to Brown |
| Hazard Information | Back Directory | [Uses]
6-?Acetyl-?8-?cyclopentyl-?5-?methylpyrido[2,?3-?d]?pyrimidine-?2,?7(1H,?8H)?-?dione is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer. |
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