| Identification | Back Directory | [Name]
Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis- | [CAS]
2173014-90-7 | [Synonyms]
Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis- | [Molecular Formula]
C12H25FOSi | [MOL File]
2173014-90-7.mol | [Molecular Weight]
232.41 |
| Hazard Information | Back Directory | [Uses]
The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from a cis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexanol allows for the straightforward application in organic synthesis, after simple deprotection. It can be utilized to prepare fluorinated analogues of known compounds. |
|
|