Identification | Back Directory | [Name]
L-Serinamide, N-[(3S)-3-methyl-1,2-dioxopentyl]-L-tyrosyl-L-asparaginyl-N-(1Z)-1-propen-1-yl-, cyclic 13,33-[(3S)-2,3-dihydro-3-hydroxy-2-oxo-1H-indole-7,3-diyl] deriv., [1(3S),3(3R)]- | [CAS]
220666-21-7 | [Synonyms]
L-Serinamide, N-[(3S)-3-methyl-1,2-dioxopentyl]-L-tyrosyl-L-asparaginyl-N-(1Z)-1-propen-1-yl-, cyclic 13,33-[(3S)-2,3-dihydro-3-hydroxy-2-oxo-1H-indole-7,3-diyl] deriv., [1(3S),3(3R)]- | [Molecular Formula]
C33H38N6O10 | [MOL File]
220666-21-7.mol | [Molecular Weight]
678.7 |
Hazard Information | Back Directory | [Definition]
ChEBI: TMC-95A is a 17-membered macrocyclic lactam that incorporates a phenol and a substituted indole moiety. It includes a R-hydroxy group at position 11 and a (3-methyl-2-oxopentanoyl)amino group at position at position 18 with a S-methyl group. It acts as a proteasome inhibitor and is obtained from Apiospora montagnei Sacc. TC 1093, isolated from a soil sample. It has a role as an antimicrobial agent, a proteasome inhibitor, an antineoplastic agent, a bacterial metabolite and a fungal metabolite. It is a macrocycle, a lactam, a secondary alcohol, a tertiary alcohol, a member of indoles and a member of phenols. |
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