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2218-68-0

2218-68-0 Structure

2218-68-0 Structure
IdentificationBack Directory
[Name]

cloral betaine
[CAS]

2218-68-0
[Synonyms]

cloral betaine
Chloral Betaine
Chloral betaine hydrate
2-(trimethylazaniumyl)acetate
2-(trimethylazaniumyl)ethanoate
2,2,2-trichloroethane-1,1-diol,2-(trimethylazaniumyl)acetate
[EINECS(EC#)]

218-722-1
[Molecular Formula]

C5H11NO2.C2H3Cl3O2
[MOL File]

2218-68-0.mol
[Molecular Weight]

282.55
Chemical PropertiesBack Directory
[Melting point ]

122.5-124.5°
Hazard InformationBack Directory
[Originator]

Beta-Chlor,Mead Johnson,US,1963
[Uses]

Sedative-hypnotic.
[Manufacturing Process]

An intimate mixture of betaine hydrate (67.5 g) and chloral hydrate (100 g) was warmed to ca. 60°C when an exothermic reaction occurred and the mixture became pasty. It was then stirred at 60°C for 30 minutes. The residue solidified on cooling and was crystallized from a small amount of water. The product separated in hard, colorless prisms of MP 122.5 to 124.5°C (corr).
[Therapeutic Function]

Sedative
Safety DataBack Directory
[Toxicity]

LD50 oral in mouse: 800mg/kg
[DEA Controlled Substances]

CSCN: 2460
CSA SCH: Schedule IV
NARC: No
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