| Identification | Back Directory | [Name]
3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- | [CAS]
2218463-17-1 | [Synonyms]
HO-(CH2CH2O)12-Bn
35-benzyloxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxa-pentatriacontan-1-ol
3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- | [Molecular Formula]
C31H56O13 | [MOL File]
2218463-17-1.mol | [Molecular Weight]
636.77 |
| Hazard Information | Back Directory | [Biological Activity]
Benzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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