Identification | Back Directory | [Name]
7H-Pyrrolo[2,3-g]benzothiazol-7-one,6,8-dihydro-(9CI) | [CAS]
222036-27-3 | [Synonyms]
6H-thiazolo[5,4-e]indol-7(8H)-one 6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one 6,8-dihydro-7H-Pyrrolo[2,3-g]benzothiazol-7-one 7H-Pyrrolo[2,3-g]benzothiazol-7-one,6,8-dihydro- 6,8-dihydropyrrolo[2,3-g][1,3]benzothiazol-7-one 7H-Pyrrolo[2,3-g]benzothiazol-7-one,6,8-dihydro-(9CI) (Z)-ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobutanoate(WX135245) | [Molecular Formula]
C9H6N2OS | [MOL File]
222036-27-3.mol | [Molecular Weight]
190.22 |
Chemical Properties | Back Directory | [Melting point ]
>150°C (dec.) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Sonicated) | [form ]
Solid | [color ]
Pale Beige |
Hazard Information | Back Directory | [Uses]
6,8-Dihydro-7H-pyrrolo[2,3-g]benzothiazol-7-one is an intermediate in synthesizing Imidazolo-oxindole PKR inhibitor C16 (PKR Inhibitor) (P572500). It is a drug which acts as a selective inhibitor of the enzyme double-stranded RNA-dependent protein kinase (PKR). It has been shown to effectively inhibit PKR function in vivo and has neuroprotective and nootropic effects in animal studies. |
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